Aiding in energy productionĬoenzyme Q10 is found within the membranes of mitochondria. What does coenzyme Q10 (ubiquinol / ubiquinone) do?Ĭoenzyme Q10 has two important functions in the body 4: 1. The average diet is estimated to provide approximately 10mg of ubiquinone per day. Organ meat (heart, liver, kidney, testes, thymus).Deficiencies in these vitamins and minerals can compromise CoQ10 production.Ĭoenzyme Q10 can be obtained in the form of ubiquinone through dietary means, although this is limited. Its production involves a multi-cascade of events that requires at least 7 vitamins - B6, Folate, C, B2, B3, B12, Pantothenic acid - as well as trace minerals such as magnesium and selenium. CoQ10 is made from the amino acids, tyrosine and phenylalanine. In order for the liver to produce CoQ10, the body has to be well-nourished. BiosynthesisĬoenzyme Q10 is synthesised in the liver. Small amounts may also be obtained from the diet. In healthy individuals, approximately 95% of the CoQ10 circulating in plasma is in the reduced form, ubiquinol.Ĭoenzyme Q10 is primarily made by the body in a process known as biosynthesis. If there are insufficient levels of ubiquinol in the body, it will reduce ubiquinone to form ubiquinol, and vice versa. This transforms ubiquinol to ubiquinone (the oxidised state). When oxidation occurs, reduced CoQ10 or ubiquinol: This transforms ubiquinone to ubiquinol (the reduced form) As such, maintaining a balance in these reactions is vital for optimal health.ĭuring the redox reaction, reduction occurs when oxidised CoQ10 (aka ubiquinone) is used by the body and reduced, which causes it to: Imbalances in cellular redox reactions are attributed to the development of several diseases. The body’s cells continually undergo redox reactions to maintain a state of balance in various chemical compounds for optimal cellular function. The main difference between them is determined by their chemical state in a biological process known as an oxidation-reduction or ‘redox’ reaction. Ubiquinol and ubiquinone are two related but chemically different forms of Coenzyme Q10, both of which play important roles within the body. Ubiquinol vs ubiquinone – what's the difference? It is so prolific that the names ubiquinol and ubiquinone are, in fact, derived from the word ' ubiquitous' - meaning ‘present everywhere’. It is found in most animal and human cells and is highly concentrated the organs and tissues 1. Issues with bioavailability and how to choose a productĬonzyme Q10 / Ubiquinone / Ubiquinol side effectsĬoenzyme Q10, also referred to as CoQ10, ubiquinol, ubiquinone or ubidecarenone is fat-soluble vitamin-like nutrient. When it comes to supplementation which is better ubiquinol or ubiquinone (CoQ10)? What are Coenzyme Q10 (ubiquinone and ubiquinol) supplements used for?ĬoQ10 for those undergoing cancer treatment What does coenzyme Q10 (ubiquinol / ubiquinone) do? Where does coenzyme Q10 / ubiquinol come from? Ubiquinol vs ubiquinone – what’s the difference?
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